Boy Or Girl? It’s In The Father’s Genes

A man’s sperm contains 22 chromosomes as well as either an X- or a Y-chromosome. Genes tell the body’s cells how to make factor There are tens of thousands of genes arranged along the chromosomes. Affected individuals are encouraged to seek genetic counseling for answers to any questions regarding the complex genetic factors involved in Swyer syndrome.

As a step toward cloning the sex determination gene in papaya, a high-density genetic mapping of the papaya genome was constructed using 1494 amplified fragment length polymorphism (AFLP) markers, five sequence-characterized amplified region (SCAR) markers, and two morphological markers.

This is called a genetic defect. The sex chromosomes began as an ordinary pair of autosomes During meiosis chromosomes replicate their DNA, pair, and exchange genes ( recombination ; red lines). Specifically, there is a gene on the Y chromosome called SRY that makes the big difference.

These XX males can frequently be shown to have inherited from their fathers an X chromosme onto which a little bit of the Y chromosome carrying SRY has been transfered by an “illegitimate” cross over. Since the mother only has X chromosomes to give, it should be obvious that it is the father’s cells that determine whether the Gender Baby will genetically be a boy or a girl.

Swyer syndrome affects girls who have an XY chromosomal makeup, no ovaries, but functional female organs including the uterus, fallopian tubes and vagina. In addition to genetic mechanisms, environmental factors may have an influence on the probability of bearing a boy versus a girl.

Women with CAIS are born with an XY chromosome pair. Also, chunks of genes stopped recombining, and by mapping their positions on the chromosome, one can guess that an event, like an inversion , may have taken place. We did a study based on parental report , and found a diagnosis of autism spectrum disorder was more common in boys with XXY and XYY than in boys with normal XY chromosome status.

Although the sorrel and Japanese hop sex chromosomes evolved much more recently (angiosperm evolved about 158-179 MYA) than the 300 million years old mammal sex chromosomes, they appear to be at a later stage of sex chromosome evolution because the two Y chromosomes do not contain sex determination genes.

Figure 4: Sex determination in humans. The Silene sex chromosomes possess these properties. The following image of cells from a female cheek swab was “borrowed” from the US Army. Typical sexual development is the result of numerous genes, and mutation in any of these genes can result in partial or complete failure of sex differentiation.

In some brain regions, the two sexes differ in patterns of acetylation or methylation of histones by several days before birth, indicating that sex-biased signals have already impacted the brain epigenome by that stage ( Tsai et al., 2009 ; Matsuda et al., 2011 ). The sex differences are dynamic in this period, with some sex differences appearing and disappearing in the course of a few days ( Matsuda et al., 2011 ). In one study, treatment of female embryos with testosterone masculinized the pattern of acetylation of histone 3 measured at birth, but did not sex-reverse the pattern of methylation of histone 3 ( Matsuda et al., 2011 ). Thus, diverse sex-biased signals, including testosterone secreted by the male, appear to sexually differentiate histone modifications during the perinatal period.

It’s thought that little pieces of the future Y started doing genetic backflips, called inversions, that made it harder to recombine, and the genetic gulf between the sexes first began to widen. Class IV is a newly proposed and speculative class, not of specific genes, but of non-coding regions of the sex chromosomes.

The paternal assignment in the Paternal Haplogroup report, however, uses DNA that is only inherited by males. In humans, hypertension is more prevalent in males than females. However, another syndrome, XY gonadal dysgenesis or the XY sex reversal syndrome(1) is convincing enough, to require that even some persons with a normal Y chromosome must be regarded as female.

While these chromosomes were once thought to be identical far back in the early history of mammals, the Y chromosome now has about 78 genes, compared with about 800 in the X chromosome. This enzyme helps produce a molecule called cytochrome c. Cytochrome c is involved in a process called oxidative phosphorylation, by which mitochondria generate adenosine triphosphate (ATP), the cell’s main energy source.

Leave a Reply

Your email address will not be published. Required fields are marked *